PAMR1_MOUSE Q8BU25
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UniProt:Q8BU25
Recommended name:Inactive serine protease PAMR1
EC number:
Alternative names:(Peptidase domain-containing protein associated with muscle regeneration 1) (Regeneration-associated muscle protease homolog)
Cleaved into:
GeneID:210622
Gene names (primary ):Pamr1
Gene names (synonym ):Ramp
Gene names (ORF ):
Length:720
Mass:80320
Sequence:MELDRWAQLGLVFLQLLLISSLPREYTVINEACPGAEWNIMCRECCEYDQIECLCPGKKEVVGYTIPCCRNEDNECDSCLIHPGCTIFENCKSCRNGSWGGTLDDFYVKGFYCAECRAGWYGGDCMRCGQVLRASKGQILLESYPLNAHCEWTIHARPGFIIQLRFGMLSLEFDYMCQYDYVEVRDGDNSDSPIIKRFCGNERPAPIRSTGSSLHVLFHSDGSKNFDGFHAVFEEITACSSSPCFHDGTCLLDTTGSFKCACLAGYTGQRCENLLEERNCSDLGGPVNGYKKITEGPGLLNERHVKIGTVVSFFCNGSYVLSGNEKRTCQQNGEWSGKQPVCMKACREPKISDLVRRRVLSMQVQSRETPLHQLYSTAFSKQKLQDASTKKPALPFGDLPPGYQHLHTQVQYECISPFYRRLGSSRRTCLRTGKWSGRAPSCIPICGKIESTPSPKTQGTRWPWQAAIYRRTSGVHDGGLHKGAWFLVCSGALVNERTVVVAAHCVTELGKATIIKTADLKVVLGKFYRDDDRDEKSIQNLRVSAIILHPNYDPILLDTDIAVLKLLDKARISTRVQPICLATTRDLSTSFQESHITVAGWNILADVRSPGFKNDTLHYGMVRVVDPMLCEEQHEDHGIPVSVTDNMFCASKDPSTPSDICTAETGGIAALSFPGRASPEPRWHLVGLVSWSYDKTCSNGLSTAFTKVLPFKDWIERNMK
Tissue specificity:Predominantly expressed in normal skeletal muscle and brain. Expression is enhanced in the regenerating area of injured skeletal muscle in mice. {ECO:0000269|PubMed:15111323}.
Induction:Down-regulated in dystrophin-mutant mdx muscle cell line. {ECO:0000269|PubMed:15111323}.
Developmental stage:
Protein families:Peptidase S1 family