ADIPL_MOUSE Q8R2Z0
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UniProt:Q8R2Z0
Recommended name：Adipolin
EC number：
Alternative names：(Adipose-derived insulin-sensitizing factor) (Complement C1q tumor necrosis factor-related protein 12)
Cleaved into：Adipolin fC1QTNF12 (Adipolin fCTRP12) (Adipolin full-length form); Adipolin gC1QTNF12 (Adipolin cleaved form) (Adipolin gCTRP12)
GeneID：67389
Gene names (primary )：C1qtnf12
Gene names (synonym )：C1qdc2 Ctrp12 Fam132a
Gene names (ORF )：
Length：308
Mass：33267
Sequence：MWAWGWAAAALLWLQTAGAGARQELKKSRQLFARVDSPNITTSNREGFPGSVKPPEASGPELSDAHMTWLNFVRRPDDGSSRKRCRGRDKKSRGLSGLPGPPGPPGPPGPPGSPGVGVTPEALLQEFQEILKEATELRFSGLPDTLLPQEPSQRLVVEAFYCRLKGPVLVDKKTLVELQGFQAPTTQGAFLRGSGLSLSLGRFTAPVSAIFQFSASLHVDHSELQGRGRLRTRDMVRVLICIESLCHRHTSLEAVSGLESNSRVFTVQVQGLLHLQSGQYVSVFVDNSSGAVLTIQNTSSFSGMLLGT
Tissue specificity：Widely expressed, with high expression in subcutaneous and epididymal white adipose tissues and brown adipose tissue. Expressed in adipocytes (at protein level). {ECO:0000269|PubMed:21849507, ECO:0000269|PubMed:22275362}.
Induction：During adipogenesis. Upon insulin treatment. Up-regulated in obeses mice. Transcription is activated by KLF3 and KLF15. {ECO:0000269|PubMed:21849507, ECO:0000269|PubMed:22275362, ECO:0000269|PubMed:23068097, ECO:0000269|PubMed:23633521, ECO:0000269|PubMed:24358263}.
Developmental stage：
Protein families：Adipolin/erythroferrone family