NOX4_MOUSE Q9JHI8
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UniProt:Q9JHI8
Recommended name：NADPH oxidase 4
EC number：EC 1.6.3.-
Alternative names：(Kidney oxidase-1) (KOX-1) (Kidney superoxide-producing NADPH oxidase) (Renal NAD(P)H-oxidase) (Superoxide-generating NADPH oxidase 4)
Cleaved into：
GeneID：50490
Gene names (primary )：Nox4
Gene names (synonym )：Renox
Gene names (ORF )：
Length：578
Mass：66519
Sequence：MAVSWRSWLANEGVKHLCLLIWLSLNVLLFWKTFLLYNQGPEYYYIHQMLGLGLCLSRASASVLNLNCSLILLPMCRTVLAYLRGSQKVPSRRTRRLLDKSKTLHITCGVTICIFSGVHVAAHLVNALNFSVNYSEDFLELNAARYQNEDPRKLLFTTIPGLTGVCMVVVLFLMVTASTYAIRVSNYDIFWYTHNLFFVFYMLLLLHVSGGLLKYQTNVDTHPPGCISLNQTSSQNMSIPDYVSEHFHGSLPRGFSKLEDRYQKTLVKICLEEPKFQAHFPQTWIWISGPLCLYCAERLYRCIRSNKPVTIISVINHPSDVMELRMIKENFKARPGQYIILHCPSVSALENHPFTLTMCPTETKATFGVHFKVVGDWTERFRDLLLPPSSQDSEILPFIHSRNYPKLYIDGPFGSPFEESLNYEVSLCVAGGIGVTPFASILNTLLDDWKPYKLRRLYFIWVCRDIQSFQWFADLLCVLHNKFWQENRPDFVNIQLYLSQTDGIQKIIGEKYHTLNSRLFIGRPRWKLLFDEIAKCNRGKTVGVFCCGPSSISKTLHSLSNRNNSYGTKFEYNKESFS
Tissue specificity：EXpressed in brain, in all layers of the cerebellum, in pyramidal cells of the Ammon horn and in Purkinje cells (at protein level). Expressed in osteoclasts, leukocytes, kidney, liver and lung. {ECO:0000269|PubMed:10869423, ECO:0000269|PubMed:11098048, ECO:0000269|PubMed:15802177}.
Induction：Upon brain ischemia it is up-regulated in ischemic tissues and more specially in neocapillaries (at protein level). Up-regulated upon hypoxia. {ECO:0000269|PubMed:15016652, ECO:0000269|PubMed:15802177}.
Developmental stage：
Protein families：