GSX2_MOUSE   P31316


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UniProt:P31316

Recommended name:GS homeobox 2

EC number:

Alternative names:(Genetic-screened homeobox 2) (Homeobox protein GSH-2)

Cleaved into:

GeneID:14843

Gene names  (primary ):Gsx2

Gene names  (synonym ):Gsh-2 Gsh2

Gene names  (ORF ):

Length:305

Mass:32167

Sequence:MSRSFYVDSLIIKDSSRPAPSLPESHPGPDFFIPLGMPSPLVMSVSGPGCPSRKSGAFCVCPLCVTSHLHSSRPPAGAGGGATGTAGAAVAGGGVAGGTGALPLLKSQFSPAPGDAQFCPRVSHAHHHHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAAAAAALGHPQHHAPVCAATTYNMSDPRRFHCLSMGGSDTSQVPNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGASRNNHTSCKCVGSQAHYARSEDEDSLSPASANEDKEISPL

Tissue specificity:

Induction:

Developmental stage:At 10.0 dpc, expressed in a band of primitive neuroepithelial cells in the neural tube, mesencephalon and telencephalon. At 11.5-13.5 dpc, expression is symmetrical, but tightly limited in areas of the forebrain, midbrain and hindbrain (PubMed:7619729). At 11 dpc, in the developing telencephalon, expressed at high levels in cells throughout the presumptive lateral ganglionic eminence (LGE), with an apparent ventral-to-dorsal gradient in expressing cell numbers. Positive cells are also scattered somewhat uniformly throughout the adjacent medial ganglionic eminence. At 12.5 dpc onward, exhibits a clear graded pattern of expression, with low levels found in cells located ventrally and the highest levels confined to those in the most dorsal portion of the LGE (at protein level) (PubMed:19709628). Expression decreases from 14.5 dpc on and becomes undetectable at 16.5 dpc (PubMed:7619729). {ECO:0000269|PubMed:19709628, ECO:0000269|PubMed:7619729}.

Protein families:Antp homeobox family


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