PTTG1_MOUSE Q9CQJ7
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UniProt:Q9CQJ7
Recommended name:Securin
EC number:
Alternative names:(Pituitary tumor-transforming gene 1 protein)
Cleaved into:
GeneID:30939
Gene names (primary ):Pttg1
Gene names (synonym ):Pttg
Gene names (ORF ):
Length:199
Mass:21725
Sequence:MATLIFVDKDNEEPGRRLASKDGLKLGTGVKALDGKLQVSTPRVGKVFNAPAVPKASRKALGTVNRVAEKPMKTGKPLQPKQPTLTGKKITEKSTKTQSSVPAPDDAYPEIEKFFPFNPLDFESFDLPEEHQISLLPLNGVPLMTLNEERGLEKLLHLGPPSPLKTPFLSWESDPLYSPPSALSTLDVELPPVCYDADI
Tissue specificity:
Induction:
Developmental stage:During the stages 11.5-13.5 dpc it is expressed in most tissues of the embryo. Within the telencephalon, it is exclusively expressed inside of the ventricular zone (VZ). The expression reaches its peak by 15.5 dpc and starts to decrease by 18.5 dpc, and is not detectable in the adult brains. Most of the cells expressing it were found in the lower part of the ventricular zone. {ECO:0000269|PubMed:10727870}.
Protein families:Securin family