CXE1_MOUSE   Q9CX92


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UniProt:Q9CX92

Recommended name:Gap junction epsilon-1 protein

EC number:

Alternative names:(Connexin-23) (Cx23)

Cleaved into:

GeneID:76743

Gene names  (primary ):Gje1

Gene names  (synonym ):Cx23 Gjf1

Gene names  (ORF ):

Length:205

Mass:23831

Sequence:MSLNYIKNFYEGCVKPPTVIGQFHTLFFGSVRMFFLGVLGFAVYGNEALHFSCDPDKREINLFCYNQFRPITPQVFWALQLVIVLLPGAIFHLYAACKSINQDCILQKPVYTVIYVLSVLLRISLEVFAFWLQIHLFGFQVKPIYLCDTESLGKKPNILKCMVPEHFEKTIFLIAMYTFTVITMVLCVAEVFEIIFRRSCFLFKR

Tissue specificity:Highly expressed in lens, where it is mainly found in lens fibers and to a lesser extent in lens epithelium (PubMed:18385072, PubMed:18849090). Weakly expressed in retina (PubMed:18849090). Not detected in other tissues tested (PubMed:18385072, PubMed:18849090). {ECO:0000269|PubMed:18385072, ECO:0000269|PubMed:18849090}.

Induction:

Developmental stage:Expressed at the posterior region of the lens vesicle at embryonic stage 11.5 dpc. Detected at the tip of elongating lens fiber cells at stage 12.5 dpc. Expressed in lens epithelial cells, and weakly in retina, at stage 15.5 dpc. {ECO:0000269|PubMed:18385072}.

Protein families:Connexin family, Beta-type (group I) subfamily


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