SNRK_MOUSE Q8VDU5
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UniProt:Q8VDU5
Recommended name:SNF-related serine/threonine-protein kinase
EC number:EC 2.7.11.1
Alternative names:(SNF1-related kinase)
Cleaved into:
GeneID:20623
Gene names (primary ):Snrk
Gene names (synonym ):
Gene names (ORF ):
Length:748
Mass:81913
Sequence:MAGFKRGYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPPRVSAGCRDLITRMLQRDPKRRASLEEIESHPWLQGVDPSPATKYNIPLVSYKNLSEEEHNSIIQRMVLGDIADRDAIVEALETNRYNHITATYFLLAERILREKQEKEIQTRSASPSNIKAQFRQSWPTKIDVPQDLEDDLTATPLSHATVPQSPARAGDNVLNGHRSKGLCDPAKKDELPELAGPALSTVPPASMKPAASGRKCLFRVEEDEEEDEEDKKPVSLSTQVVLRRKPSVTNRLTSRKSAPVLNQIFEEGESDDEFDMDENLPPKLSRLKMNIASPGTVHKRYHRRKSQGRGSSCSSSETSDDDSESRRRLDKDSGFAYSWHRRDSSEGPPGSEGDGGGQSKPSSGGGVDKASPGEQGTGGGSQGGSGGTPSGTAGSSRRCAGPDSSSPSPASASAAPRGAELVQSLKLVSLCLGSQLHGAKYILDPQKALFSSVKVQEKSTWKMCISAPGPSPSADLDPVRTKKLRNNALQLPLCEKTISVNIQRSRKEGLLCASSPASCCHVI
Tissue specificity:Ubiquitously expressed in all tissues examined. {ECO:0000269|PubMed:12234663}.
Induction:
Developmental stage:Expressed from day 8 dpc along the epithelium of the differentiating neural tube. Expression persists along the dorsal axis until 12.5 dpc, but becomes progressively restricted to the more caudal part of the neural tube with much stronger intensity in the caudal neuropore. Also observed in the endoderm of the primitive gut between 8.5 and 11.5 dpc, at 10.5 dpc, in the endocardium and pericardium of the developing heart, and in both the endothelium and blood cells clustered at the ventral part of the dorsal aorta. Later in development (12.5 dpc), expressed in the endocardium and the interventricular septum of the heart. {ECO:0000269|PubMed:12234663}.
Protein families:Protein kinase superfamily, CAMK Ser/Thr protein kinase family