DPPA2_MOUSE Q9CWH0
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UniProt:Q9CWH0
Recommended name:Developmental pluripotency-associated protein 2
EC number:
Alternative names:(Embryonic stem cell-associated transcript 15-2 protein) (ECAT15-2) (Pluripotent embryonic stem cell-related gene 1 protein)
Cleaved into:
GeneID:73703
Gene names (primary ):Dppa2
Gene names (synonym ):Phsecrg1
Gene names (ORF ):
Length:301
Mass:34116
Sequence:MSYFGLETFNENQSEENLDEESVILTLVPFKEEEEPNTDYATQSNVSSSTLDHTPPARSLVRHAGIKHPTRTIPSTCPPPSLPPIRDVSRNTLREWCRYHNLSTDGKKVEVYLRLRRHSYSKQECYIPNTSREARMKQGPKKSKIVFRGIGPPSGCQRKKEESGVLEILTSPKESTFAAWARIAMRAAQSMSKNRCPLPSNVEAFLPQATGSRWCVVHGRQLPADKKGWVRLQFLAGQTWVPDTPQRMNFLFLLPACIIPEPGVEDNLLCPECVHSNKKILRNFKIRSRAKKNALPPNMPP
Tissue specificity:Not detected in adult tissues. {ECO:0000269|PubMed:12620990}.
Induction:
Developmental stage:Expressed in 4-cell embryo, morula and blastocyst. At 7.5 dpc, detected in the epiblast. At 10.0 dpc, expressed in the primordial germ cells. Expression decreases at 12.0 dpc in the embryonic gonads. At 14.5 dpc, expression is restricted to testis. 6 days after birth, still detected in primitive type A spermatogonia. Expressed in undifferentiated embryonic stem cells, but expression rapidly decreases upon differentiation. {ECO:0000269|PubMed:12620990, ECO:0000269|PubMed:21896782}.
Protein families: