OLIG1_MOUSE Q9JKN5
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UniProt:Q9JKN5
Recommended name：Oligodendrocyte transcription factor 1
EC number：
Alternative names：(Oligo1) (Oligodendrocyte-specific bHLH transcription factor 1)
Cleaved into：
GeneID：50914
Gene names (primary )：Olig1
Gene names (synonym )：
Gene names (ORF )：
Length：260
Mass：27141
Sequence：MYYAISQARVNAAPATMLRPQRPGDVQLGASLYELVGYRQPPISSSSSSSSSTASLLPKPAREKAEAPLAEPRGPAPESGGARADAKEEQQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRRALGDGAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPETLRPTKYLSLALDEPPCGQFSLPAGGAGSPGLCSCAVCKFPHLVPAGLGLAAVQAQFSK
Tissue specificity：Expressed specifically in brain. {ECO:0000269|PubMed:11091082}.
Induction：By SHH. {ECO:0000269|PubMed:10719888}.
Developmental stage：Expressed in the ventral spinal cord as early as 9.5 dpc. Expression declines to undetectable levels by 10.5 dpc and reappears in a narrow zone within the ventral neuroepithelium of the spinal cord. In the 14.5 dpc spinal cord, expressed in the oligodendrocyte progenitors of the ventral ventricular zone, but not dorsal root ganglia Schwann cells. Also expressed scattered in the mantle zone, likely corresponding to oligodendrocyte progenitors migrating out from their site of origin. By 15.5 dpc, dispersed throughout the gray matter, with little or no residual expression in the ventricular zone. In the postnatal brain, present preferentially in the white matter, such as corpus callosum and cerebellar medulla. Expressed in the olfactory epithelium from 11.5dpc onward. {ECO:0000269|PubMed:10719889}.
Protein families：