ADA_MOUSE P03958
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UniProt:P03958
Recommended name:Adenosine deaminase
EC number:EC 3.5.4.4
Alternative names:(Adenosine aminohydrolase)
Cleaved into:
GeneID:11486
Gene names (primary ):Ada
Gene names (synonym ):
Gene names (ORF ):
Length:352
Mass:39992
Sequence:MAQTPAFNKPKVELHVHLDGAIKPETILYFGKKRGIALPADTVEELRNIIGMDKPLSLPGFLAKFDYYMPVIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVDPMPWNQTEGDVTPDDVVDLVNQGLQEGEQAFGIKVRSILCCMRHQPSWSLEVLELCKKYNQKTVVAMDLAGDETIEGSSLFPGHVEAYEGAVKNGIHRTVHAGEVGSPEVVREAVDILKTERVGHGYHTIEDEALYNRLLKENMHFEVCPWSSYLTGAWDPKTTHAVVRFKNDKANYSLNTDDPLIFKSTLDTDYQMTKKDMGFTEEEFKRLNINAAKSSFLPEEEKKELLERLYREYQ
Tissue specificity:Detected in brain neurons in the median emninence (at protein level) (PubMed:8783262). Expressed in secondary deciduum (at protein level) (PubMed:9272950). Found in all tissues, occurs in large amounts in T-lymphocytes and, at the time of weaning, in gastrointestinal tissues. {ECO:0000269|PubMed:8783262, ECO:0000269|PubMed:9272950}.
Induction:
Developmental stage:Expressed in trophoblast at 7.5 dpc and 9.5 dpc. {ECO:0000269|PubMed:9272950}.
Protein families:Metallo-dependent hydrolases superfamily, Adenosine and AMP deaminases family