CAVN4_MOUSE A2AMM0
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UniProt:A2AMM0
Recommended name:Caveolae-associated protein 4
EC number:
Alternative names:(Muscle-related coiled-coil protein) (Muscle-restricted coiled-coil protein)
Cleaved into:
GeneID:68016
Gene names (primary ):Cavin4
Gene names (synonym ):Murc
Gene names (ORF ):
Length:362
Mass:41008
Sequence:MEHNGSASNAGKIHQNRLSSVTEDEDQDAALTIVTVLDRVASVVDSVQASQKRIEERHREMGNAIKSVQIDLLKLSQSHSNTGYVVNKLFEKTRKVSAHIKDVKARVEKQQVRVTKVETKQEEIMKKNKFRVVIFQEDIPCPASLSVVKDRSLPENQEEAEEVFDPPIELSSDEEYYVEESRSARLRKSGKEHIDHIKKAFSRENMQKTRQTLDKKVSGIRTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISSAAPSKEAFKIRSLRKAKDPKAEGQEVDRGMGVDIISGSLALGPIHEFHSDEFSETEKEVTKGGYSPQEGGDPPTPEPLKVTFKPQVRVEDDESLLLELKQSS
Tissue specificity:Abundantly expressed in cardiac and skeletal muscle (at protein level). Weaker expression in aorta and lung. In heart, expressed in cardiomyocytes and vascular smooth muscle cells but not in other surrounding cells including vascular endothelial cells. {ECO:0000269|PubMed:18332105, ECO:0000269|PubMed:19546242}.
Induction:Up-regulated in response to cardiac hypertrophy. {ECO:0000269|PubMed:18332105}.
Developmental stage:Expression increases during development from embryo to adult. {ECO:0000269|PubMed:18332105}.
Protein families:CAVIN family