FADS2_MOUSE Q9Z0R9
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UniProt:Q9Z0R9
Recommended name：Acyl-CoA 6-desaturase
EC number：EC 1.14.19.3
Alternative names：(Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase) (Fatty acid desaturase 2)
Cleaved into：
GeneID：56473
Gene names (primary )：Fads2
Gene names (synonym )：Fadsd2
Gene names (ORF )：
Length：444
Mass：52387
Sequence：MGKGGNQGEGSTERQAPMPTFRWEEIQKHNLRTDRWLVIDRKVYNVTKWSQRHPGGHRVIGHYSGEDATDAFRAFHLDLDFVGKFLKPLLIGELAPEEPSLDRGKSSQITEDFRALKKTAEDMNLFKTNHLFFFLLLSHIIVMESLAWFILSYFGTGWIPTLVTAFVLATSQAQAGWLQHDYGHLSVYKKSIWNHVVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDIKSLHVFVLGEWQPLEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMISRRDWVDLAWAISYYMRFFYTYIPFYGILGALVFLNFIRFLESHWFVWVTQMNHLVMEIDLDHYRDWFSSQLAATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALIDIVSSLKKSGELWLDAYLHK
Tissue specificity：Highly expressed in the adrenal gland, liver, brain, and testis, tissues where lipogenesis and steroidogenesis are active. Also detected in lung, heart, and skeletal muscle. {ECO:0000269|PubMed:11792729, ECO:0000269|PubMed:9867867}.
Induction：Induced by dietary PUFA-deficient diet. Induced by a fat-free diet and by a diet containing triolein (18:1n-9) as the only fat source. Down-regulated in liver by dietary PUFA. {ECO:0000269|PubMed:11792729, ECO:0000269|PubMed:9867867}.
Developmental stage：Found in 13-day-old embryo heart.
Protein families：Fatty acid desaturase type 1 family