ZDH17_MOUSE Q80TN5
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UniProt:Q80TN5
Recommended name：Palmitoyltransferase ZDHHC17
EC number：EC 2.3.1.225
Alternative names：(Acyltransferase ZDHHC17) (DHHC domain-containing cysteine-rich protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Zinc finger DHHC domain-containing protein 17)
Cleaved into：
GeneID：320150
Gene names (primary )：Zdhhc17
Gene names (synonym )：Hip14 Kiaa0946
Gene names (ORF )：
Length：632
Mass：72621
Sequence：MQREEGFNTKMADGPDEYETETGCVPLLHPEEIKPQSHYNHGYGEPLGRKTHIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGGNVDAQNVKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLDIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCVSYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFHFLWVAVLLMCQLYQITCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV
Tissue specificity：Expressed in liver, testis, kidney, heart, pancreas and brain. Highest expression was seen in the brain. Localized predominantly in the perinuclear regions of neurons from the cortex, striatum and hippocampus. Colocalized with HTT in the medium spiny neurons of the striatum and the spiny neurons that project into the globus pallidus. {ECO:0000269|PubMed:12393793}.
Induction：Up-regulated by low extracellular Mg(2+). {ECO:0000269|PubMed:18794299}.
Developmental stage：Highly expressed in neurons during their differentiation. {ECO:0000269|PubMed:26232532}.
Protein families：DHHC palmitoyltransferase family, AKR/ZDHHC17 subfamily