FOXO1_MOUSE Q9R1E0
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UniProt:Q9R1E0
Recommended name:Forkhead box protein O1
EC number:
Alternative names:(Forkhead box protein O1A) (Forkhead in rhabdomyosarcoma)
Cleaved into:
GeneID:56458
Gene names (primary ):Foxo1
Gene names (synonym ):Fkhr Foxo1a
Gene names (ORF ):
Length:652
Mass:69518
Sequence:MAEAPQVVETDPDFEPLPRQRSCTWPLPRPEFNQSNSTTSSPAPSGGAAANPDAAASLASASAVSTDFMSNLSLLEESEDFARAPGCVAVAAAAAASRGLCGDFQGPEAGCVHPAPPQPPPTGPLSQPPPVPPSAAAAAGPLAGQPRKTSSSRRNAWGNLSYADLITKAIESSAEKRLTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIRVQNEGTGKSSWWMLNPEGGKSGKSPRRRAASMDNNSKFAKSRGRAAKKKASLQSGQEGPGDSPGSQFSKWPASPGSHSNDDFDNWSTFRPRTSSNASTISGRLSPIMTEQDDLGDGDVHSLVYPPSAAKMASTLPSLSEISNPENMENLLDNLNLLSSPTSLTVSTQSSPGSMMQQTPCYSFAPPNTSLNSPSPNYSKYTYGQSSMSPLPQMPMQTLQDSKSSYGGLNQYNCAPGLLKELLTSDSPPHNDIMSPVDPGVAQPNSRVLGQNVMMGPNSVMPAYGSQASHNKMMNPSSHTHPGHAQQTASVNGRTLPHVVNTMPHTSAMNRLTPVKTPLQVPLSHPMQMSALGSYSSVSSCNGYGRMGVLHQEKLPSDLDGMFIERLDCDMESIIRNDLMDGDTLDFNFDNVLPNQSFPHSVKTTTHSWVSG
Tissue specificity:Expressed in liver, white and brown adipose tissues (at protein level). {ECO:0000269|PubMed:17627282, ECO:0000269|PubMed:22510882}.
Induction:Expression is regulated by KRIT1 (PubMed:20668652). Transiently up-regulated during adipogenesis (at protein level) (PubMed:18388859). {ECO:0000269|PubMed:18388859, ECO:0000269|PubMed:20668652}.
Developmental stage:In liver, barely expressed at 14.5 dpc, expression dramatically increases at 18.5 dpc. Abundantly expressed in neonate liver but levels strongly decrease in adult liver (at protein level). {ECO:0000269|PubMed:17627282}.
Protein families: