ANO3_MOUSE A2AHL1
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UniProt:A2AHL1
Recommended name:Anoctamin-3
EC number:
Alternative names:(Transmembrane protein 16C)
Cleaved into:
GeneID:228432
Gene names (primary ):Ano3
Gene names (synonym ):Tmem16c
Gene names (ORF ):
Length:981
Mass:114568
Sequence:MVHHSGSIQSFKQQKGMNISKSEITTEASLKPSRRSLPCLAQSYAHSKSLSQSASLFQSTESESQAPTSVTFLSADKPEHVTSEESRKDSTLKCSFADLSDFCLALGKDKDYLDESEHANYDRSRLLNDFVTKDKPASKTKLSKNDMSYIASSGLLFKDGKKRIDYILVYRKTNIQYDKRNTFEKNLRAEGLMLEKEPAIANPDIMFIKIHIPWDTLCKYAERLNIRVPFRKKCYYTDQKNKSKSRVQNYFKRIKKWMSQNPMVLDKSAFPELEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYENGISKVGIRKLITNGSYIAAFPPHEGAYKSSLPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRMYFGEKIGLYFAWLGWYTGMLIPAAVVGLCVFFYGLVTMNESQVSQEICKATEVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAKYYRMEVINPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAVFAVVVYRLVVMEQFASFKWNFVKQHWQFATSGAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFERWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRGIQDASIPQWENDWNLQPMNIHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVKQNENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDIPKGLRERIRREKYLVQEMMYEAELEHLQQQRRKSGQPIHHEWP
Tissue specificity:Predominantly expressed in neuronal tissues. Expressed in brain. {ECO:0000269|PubMed:20056604, ECO:0000269|PubMed:23532839}.
Induction:
Developmental stage:In the developing gastrointestinal tract, expressed in the intestinal epithelium at 14.5 dpc and in an incomplete ring of cells in the mesenchyme of the esophagus, stomach and small intestine at 16.5 dpc. In the developing skeleton, expressed in the perichondria of the neural arch of developing vertebrae at 14.5 dpc and 16.5 dpc. At 14.5 dpc, also expressed in perichondria of developing ribs. At 14.5 dpc and 16.5 dpc, detected in dorsal root ganglia and neural tube. In developing skin, expression is detected in the most suprabasal layers at 16.5 dpc. Not detected in the lung at 14.5 dpc or 16.5 dpc. {ECO:0000269|PubMed:18729231}.
Protein families:Anoctamin family