EKI2_MOUSE A7MCT6
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UniProt:A7MCT6
Recommended name:Ethanolamine kinase 2
EC number:EC 2.7.1.82
Alternative names:(EKI 2) (Ethanolamine kinase-like protein)
Cleaved into:
GeneID:214253
Gene names (primary ):Etnk2
Gene names (synonym ):Tuc1
Gene names (ORF ):
Length:385
Mass:44567
Sequence:MAVPPSAPVPCSPFYLRRQEPCPQCSWSMEEKAVASAGCWEPPGPPRAAVPCFSVTVEQDDILPGALRLIRELRPHWKPEQVRTKRFKDGITNKLLACYVEEDMRDCVLVRVYGERTELLVDRENEVRNFQLLRAHGCAPKLYCTFQNGLCYEYVQGVALGPEHIREPQLFRLIALEMAKIHTIHANGSLPKPTLWHKMHRYFTLVKDEISPSLSADVPKVEVLEQELAWLKEHLSQLDSPVVFCHNDLLCKNIIYDSDKGRVCFIDYEYAGYNYQAFDIGNHFNEFAGVNVVDYSRYPARETQVQWLRYYLEAQKGTAASPREVERLYAQVNKFALASHFFWALWALIQNQYSTISFDFLRYAVIRFNQYFKVKPQVSALEMPK
Tissue specificity:Expressed in testis and liver. Low expression in ovary and kidney. {ECO:0000269|PubMed:15161093, ECO:0000269|PubMed:16861741, ECO:0000269|PubMed:18755794}.
Induction:
Developmental stage:The expression is restricted to the gonads during the sex determination period and throughout embryogenesis. In developing testis, the expression is found only in the Sertoli cells. The expression is strongest at day 11.5, more intense in the testis than the ovary. From 12.5 dpc the expression in the ovary is reduced and disappears. The expression at day 13.5 dpc is restricted to the testis cords. {ECO:0000269|PubMed:15161093}.
Protein families:Choline/ethanolamine kinase family