Recombinant Human BCAS2 (C-6His, N-T7 tag)

Recombinant Human BCAS2 (C-6His, N-T7 tag)

Size1:10μg price1:$168
Size2:50μg price2:$465
Size3:500μg price3:$2350 SKU: PEH0136 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Human BCAS2 (C-6His, N-T7 tag)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human Breast Carcinoma-Amplified Sequence 2 is produced by our E.coli expression system and the target gene encoding Ala2-Phe225 is expressed with a T7 tag at the N-terminus, 6His tag at the C-terminus.

Accession #

O75934

Host

E.coli

Species

Human

Predicted Molecular Mass

28.58 KDa

Buffer

Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, 2mM DTT, pH 8.0.

Form

Lyophilized

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

Pre-mRNA-Splicing Factor SPF27; Breast Carcinoma-Amplified Sequence 2; DNA Amplified in Mammary Carcinoma 1 Protein; Spliceosome-Associated Protein SPF 27; BCAS2; DAM1

 

Background

Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell lines. BCAS2 is a component of the spliceosome, taking part in the removal of introns from mRNA precursors. BCAS2 interacts with estrogen receptor alpha and beta, thyroid hormone receptor beta, peroxisome proliferator-activated receptor gamma. BCAS2 functions as an ER co-activator and is capable of enhancing ER-mediated transcription.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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