Alternative Names
Asialoglycoprotein Receptor 1; ASGP-R 1; ASGPR 1; C-Type Lectin Domain Family 4 Member H1; Hepatic Lectin H1; HL-1; ASGR1; CLEC4H1
Background
Asialoglycoprotein Receptor 1 (ASGPR1) is an endocytic recycling receptor, belongs to the long-form subfamily of the C-type/Ca2+-dependent lectin family. ASGPR consists of two noncovalently-linked subnits, ASGPR1 and ASGPR2. ASGPR1 mediates the endocytosis of plasma glycoproteins, recognizes terminal galactose and N-acetylgalactosamine units. When the ligand binds to to ASGPR1, results in the complex is internalized and transported to a sorting organelle, then ASGPR1 and ligand can be disassociated, ASGPR1 returns to the cell membrane surface.
Note
For Research Use Only , Not for Diagnostic Use.