Abin-2 Rabbit Polyclonal Antibody

Abin-2 Rabbit Polyclonal Antibody

Size1:50μl Price1:$118
Size2:100μl Price2:$220
Size3:500μl Price3:$980
SKU: APRab06450 Category: Polyclonal Antibody Tags: , ,

Datasheet

Summary

Production Name

Abin-2 Rabbit Polyclonal Antibody

Description

Rabbit Polyclonal Antibody

Host

Rabbit

Application

IHC,

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Purification

Affinity purification

 

Immunogen

Gene Name

TNIP2 ABIN2 FLIP1

Alternative Names

TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2;ABIN-2;Fetal liver LKB1-interacting protein)

Gene ID

79155

SwissProt ID

Q8NFZ5

 

Application

Dilution Ratio

IHC-p 1:50-200, ELISA 1:10000-20000.

Molecular Weight

 

Background

This gene encodes a protein which acts as an inhibitor of NFkappaB activation. The encoded protein is also involved in MAP/ERK signaling pathway in specific cell types. It may be involved in apoptosis of endothelial cells. Alternative splicing results in multiple transcript variants. A pseudogene related to this gene is located on the X chromosome.[provided by RefSeq, May 2014],function:Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation.,subunit:Interacts with STK11, TNFAIP3, IKBKG, NFKB1, MAP3K8 and RIPK1.,tissue specificity:Ubiquitously expressed in all tissues examined.,

 

Research Area