Recombinant Human DLL3 (C-6His)

Recombinant Human DLL3 (C-6His)

Size1:10μg price1:$89
Size2:50μg price2:$248
Size3:500μg price3:$1980 SKU: PHH2462 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Human DLL3 (C-6His)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human Delta-like protein 3 is produced by our Mammalian expression system and the target gene encoding Ala27-Leu492 is expressed with a 6His tag at the C-terminus.

Accession #

Q9NYJ7

Host

Human Cells

Species

Human

Predicted Molecular Mass

49.4 KDa

Buffer

Supplied as a 0.2 μm filtered solution of 50 mM Tris-HCl, 150 mM NaCl, 0.1 M Glycine, 0.2 M Arg, 5% Trehalose, pH7.5.

Form

Liquid

Shipping

The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

 

 

 

Alternative Names

Delta-like protein 3; Drosophila Delta homolog 3; Delta3; DLL3

 

Background

Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 is highly expressed in tumor cells and could be involved in the modification of tumor (immune) microenvironment. Neuroendocrine carcinomas are very aggressive tumors with few treatment options. DLL3 seems to be an optimal target for therapeutic intervention, as it is expressed mainly on the membrane of tumor cells with neuroendocrine origin.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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