Recombinant Cynomolgus EDIL3 (C-6His)

Recombinant Cynomolgus EDIL3 (C-6His)

Size1:10μg price1:$89
Size2:50μg price2:$248
Size3:500μg price3:$1980 SKU: PHV2438 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Cynomolgus EDIL3 (C-6His)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

Please contact with the lab for this information

Construction

Recombinant Cynomolgus EGF-like repeat and discoidin I-like domain-containing protein 3 is produced by our Mammalian expression system and the target gene encoding Asp24-Glu480 is expressed with a 6His tag at the C-terminus.

Accession #

A0A2K5WYU3

Host

Human Cells

Species

Cynomolgus

Predicted Molecular Mass

52.1 kDa

Buffer

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 300mM NaCl, pH8.0.

Form

Liquid

Shipping

The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

 

 

 

Alternative Names

0

 

Background

EGF-Like Repeat and Discoidin I-Like Domain-Containing Protein 3 (EDIL3) is a 52 kDa extracellular matrix protein that is expressed by endothelial tissues during embryonic vascular development. EDIL3 becomes quiescent at the time of birth, and is no longer expressed in normal adult tissues. EDIL3 has been found to be re-expressed in a number of human tumors as well as in ischemic muscles and ischemic brain tissue, which may play an important role in adult angiogenesis. EDIL3 promotes adherence and migration of endothelial cells, and acts as an endothelial cell survival agent through upregulation of Bcl-2 expression. EDIL3 has also been shown to be an endogenous inhibitor of inflammatory cell recruitment by interfering with the integrin LFA-1-dependent leukocyte-endothelial adhesion. Human EDIL3 is synthesized as a precursor with a 16 amino acid signal sequence and a 464 amino acid mature chain.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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