Recombinant Human PSMA (N-Fc)

Recombinant Human PSMA (N-Fc)

Size1:10μg price1:$89
Size2:50μg price2:$248
Size3:500μg price3:$2150 SKU: PHH2436 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Human PSMA (N-Fc)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

Please contact with the lab for this information

Construction

Recombinant Human Glutamate carboxypeptidase 2 is produced by our Mammalian expression system and the target gene encoding Lys44-Ala750 is expressed with a human IgG1 Fc tag at the N-terminus.

Accession #

AAC83972.1

Host

Human Cells

Species

Human

Predicted Molecular Mass

105.3 kDa

Buffer

Lyophilized from a 0.2 μm filtered solution of 20mM MES,150mM NaCl, pH5.5.

Form

Lyophilized

Shipping

The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

0

 

Background

Glutamate carboxypeptidase 2, also known as FOLH1, PSMA, belongs to the M28B subfamily and the peptidase M28 family. It is highly expressed in prostate epithelium and can be detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon and brain (at protein level). PSMA is used as a diagnostic and prognostic indicator of prostate cancer, and as a possible marker for various neurological disorders such as schizophrenia, Alzheimer disease and Huntington disease. It has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity and has a preference for tri-alpha-glutamate peptides. PSMA involves in prostate tumor progression and also exhibits a dipeptidyl-peptidase IV type activity. In vitro, PSMA cleaves Gly-Pro-AMC. PSMA is stable at pH greater than 6.5.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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