Recombinant Human UCH-L1 (C-6His)

Recombinant Human UCH-L1 (C-6His)

Size1:10μg price1:$66
Size2:50μg price2:$186
Size3:500μg price3:$930 SKU: PEH1778 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Human UCH-L1 (C-6His)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 is produced by our E.coli expression system and the target gene encoding Met1-Ala223 is expressed with a 6His tag at the C-terminus.

Accession #

P09936

Host

E.coli

Species

Human

Predicted Molecular Mass

25.89 KDa

Buffer

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 250mM NaCl, 10% Trehalose, 0.05% Tween80, 1mM TCEP, pH8.5.

Form

Liquid

Shipping

The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

 

 

 

Alternative Names

Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1; UCH-L1; Neuron Cytoplasmic Protein 9.5; PGP 9.5; PGP9.5; Ubiquitin Thioesterase L1; UCHL1

 

Background

Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 (UCHL1) belongs to the Peptidase C12 family. UCHL1 is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. UCHL1 is a component of the ubiquitin system, which has a fundamental role in regulating various biological activities. UCHL1 is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. UCHL1 also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer of UCHL1 may have ATP-independent ubiquitin ligase activity.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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