Recombinant Mouse 4-1BB (C-Fc)

Recombinant Mouse 4-1BB (C-Fc)

Size1:10μg price1:$89
Size2:50μg price2:$248
Size3:500μg price3:$1240
SKU: PHM1696 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Mouse 4-1BB (C-Fc)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Mouse 4-1BB ligand receptor is produced by our Mammalian expression system and the target gene encoding Val24-Leu187 is expressed with a human IgG1 Fc tag at the C-terminus.

Accession #

P20334

Host

Human Cells

Species

Mouse

Predicted Molecular Mass

44.7 KDa

Buffer

Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Form

Liquid

Shipping

The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

 

 

 

Alternative Names

Secreted CD137 antigen ;Tumor necrosis factor receptor superfamily member 9 ;Tnfrsf9

 

Background

Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9/4-1BBL, it can activate T cells and the cross-linking of this protein can enhance T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.

 

Note

For Research Use Only , Not for Diagnostic Use.