OGFR Rabbit Polyclonal Antibody

OGFR Rabbit Polyclonal Antibody

Size1:50μl Price1:$118
Size2:100μl Price2:$220
Size3:500μl Price3:$980
SKU: APRab15121 Category: Polyclonal Antibody Tags: , ,

Datasheet

Summary

Production Name

OGFR Rabbit Polyclonal Antibody

Description

Rabbit Polyclonal Antibody

Host

Rabbit

Application

WB

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Purification

Affinity purification

 

Immunogen

Gene Name

OGFR

Alternative Names

OGFR; Opioid growth factor receptor; OGFr; Protein 7-60; Zeta-type opioid receptor

Gene ID

11054

SwissProt ID

Q9NZT2

 

Application

Dilution Ratio

WB 1:500-1:2000. ELISA: 1:20000.

Molecular Weight

90kD

 

Background

The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported. [provided by RefSeq, Jul 2008],function:Receptor for opioid growth factor (OGF), also known as Met-enkephalin. Seems to be involved in growth regulation.,online information:OGFr entry,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the opioid growth factor receptor family.,subcellular location:The OGF/OGFR complex is probably translocated to the nucleus.,tissue specificity:Highly expressed in the heart and liver, moderately in skeletal muscle and kidney and to a lesser extent in brain and pancreas. Expressed in fetal tissues including liver and kidney.,

 

Research Area