Cyclin M2 Rabbit Polyclonal Antibody

Cyclin M2 Rabbit Polyclonal Antibody

Size1:50μl Price1:$118
Size2:100μl Price2:$220
Size3:500μl Price3:$980
SKU: APRab09605 Category: Polyclonal Antibody Tags: , ,

Datasheet

Summary

Production Name

Cyclin M2 Rabbit Polyclonal Antibody

Description

Rabbit Polyclonal Antibody

Host

Rabbit

Application

WB

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Purification

Affinity purification

 

Immunogen

Gene Name

CNNM2

Alternative Names

CNNM2; ACDP2; Metal transporter CNNM2; Ancient conserved domain-containing protein 2; Cyclin-M2

Gene ID

54805

SwissProt ID

Q9H8M5

 

Application

Dilution Ratio

WB 1:500-1:2000. ELISA: 1:10000.

Molecular Weight

100kD

 

Background

cyclin and CBS domain divalent metal cation transport mediator 2(CNNM2) Homo sapiens This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play an important role in magnesium homeostasis by mediating the epithelial transport and renal reabsorption of Mg2+. Mutations in this gene are associated with renal hypomagnesemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],function:Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+).,miscellaneous:Shares weak sequence similarity with the cyclin family, explaining its name. However it has no cyclin-like function in vivo.,similarity:Belongs to the ACDP family.,similarity:Contains 2 CBS domains.,tissue specificity:Widely expressed. Expressed at higher level in brain, kidney and placenta, while it is weakly expressed in skeletal muscle.,

 

Research Area