ALKBH4 Rabbit Monoclonal Antibody

ALKBH4 Rabbit Monoclonal Antibody

Size1:50μl Price1:$188
Size2:100μl Price2:$338
Size3:500μl Price3:$1200
SKU: AMRe01631 Category: Rabbit Monoclonal Antibody Tags: , , ,

Datasheet

Summary

Production Name

ALKBH4 Rabbit Monoclonal Antibody

Description

Recombinant Rabbit Monoclonal antibody

Host

Rabbit

Application

WB

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purified

 

Immunogen

Gene Name

ALKBH4

Alternative Names

ABH4

Gene ID

54784

SwissProt ID

Q9NXW9

 

Application

Dilution Ratio

WB: 1/500-1/1000

Molecular Weight

Calculated MW: 34 kDa; Observed MW: 34 kDa

 

Background

Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation.

 

Research Area

Epigenetics and Nuclear Signaling