NOP10 Rabbit Monoclonal Antibody

NOP10 Rabbit Monoclonal Antibody

Size1:50μl Price1:$188
Size2:100μl Price2:$338
Size3:500μl Price3:$1200
SKU: AMRe03118 Category: Rabbit Monoclonal Antibody Tags: , , , ,

Datasheet

Summary

Production Name

NOP10 Rabbit Monoclonal Antibody

Description

Recombinant Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,IHC

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purified

 

Immunogen

Gene Name

NOP10

Alternative Names

DKCB1; NOLA3; NOP10P

Gene ID

55505

SwissProt ID

Q9NPE3

 

Application

Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100

Molecular Weight

Calculated MW: 8 kDa; Observed MW: 8 kDa

 

Background

This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA2 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nop10p.

 

Research Area

Epigenetics and Nuclear Signaling