Summary
| Production Name | PRMT5 Rabbit Monoclonal Antibody |
| Description | Recombinant Rabbit Monoclonal antibody |
| Host | Rabbit |
| Application | WB |
| Reactivity | Human, Mouse, Rat |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG |
| Clonality | Monoclonal Antibody |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| Purification | Affinity Purified |
Immunogen
| Gene Name | PRMT5 |
| Alternative Names | HRMT1L5; IBP72; JBP1; SKB1; SKB1Hs; PRMT5; Skb1Hs Methyltransferase |
| Gene ID | 10419 |
| SwissProt ID | O14744 |
Application
| Dilution Ratio | WB: 1/500-1/1000 |
| Molecular Weight | Calculated MW:73 kDa;Observed MW: 73 kDa |
Background
Involved in regulation of cell cycle progression through G2 by negatively regulating Swe1p, a protein tyrosine kinase that phosphorylates and inhibits Cdc28p. An Hsl7p homologue, Skb1, was identified in fission yeast by virtue of its yeast two-hybrid interaction with Shk1p, a p21 (cdc42p/Rac) activated kinase (PAK).
Research Area
Epigenetics and Nuclear Signaling
