Alternative Names
Pregnancy specific beta-1-glycoprotein 2; PSBG2; Pregnancy-specific beta-1 glycoprotein E; pregnancy-specific beta-1-glycoprotein 2; pregnancy-specific beta-1-glycoprotein 7; PSG2
Background
PSG2 is a secreted protein that in humans is encoded by the PSG2 gene. It is a member of the human pregnancy-specific glycoproteins (PSGs) family. These proteins are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. PSG2 consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. It has an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain.
Note
For Research Use Only , Not for Diagnostic Use.
