PLK1 Rabbit Monoclonal Antibody

PLK1 Rabbit Monoclonal Antibody

Size1:50μl Price1:$188
Size2:100μl Price2:$338
Size3:500μl Price3:$1200 SKU: AMRe03292 Category: Rabbit Monoclonal Antibody Tags: , , , ,

Datasheet

Summary

Production Name

PLK1 Rabbit Monoclonal Antibody

Description

Recombinant Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,ICC/IF

Reactivity

Human,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purified

 

Immunogen

Gene Name

PLK1

Alternative Names

PLK1; PLK; Serine/threonine-protein kinase PLK1; Polo-like kinase 1; PLK-1; Serine/threonine-protein kinase 13; STPK13

Gene ID

5347

SwissProt ID

P53350

 

Application

Dilution Ratio

WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Molecular Weight

Calculated MW: 68 kDa; Observed MW: 68 kDa

 

Background

Required for recovery after DNA damage checkpoint and entry into mitosis. Required for kinetochore localization of BUB1B. Phosphorylates SGOL1. Required for spindle pole localization of isoform 3 of SGOL1 and plays a role in regulating its centriole cohesion function. Phosphorylates BORA, and thereby promotes the degradation of BORA. Contributes to the regulation of AURKA function. Regulates TP53 stability through phosphorylation of TOPORS.

 

Research Area

Cell Biology

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