MSH6 Rabbit Monoclonal Antibody-Rabbit Monoclonal Antibody-EnkiLife-Recombinant Proteins,Antibodies,Kits,Cell Biology

MSH6 Rabbit Monoclonal Antibody

Summary

Production Name	MSH6 Rabbit Monoclonal Antibody
Description	Recombinant Rabbit Monoclonal antibody
Host	Rabbit
Application	WB,ICC/IF
Reactivity	Human,Mouse

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification	Affinity Purified

Immunogen

Gene Name	MSH6
Alternative Names	MSH6; GTBP; DNA mismatch repair protein Msh6; hMSH6; G/T mismatch-binding protein; GTBP; GTMBP; MutS-alpha 160 kDa subunit; p160
Gene ID	2956
SwissProt ID	P52701

Application

Dilution Ratio	WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Molecular Weight	Calculated MW: 153 kDa; Observed MW: 163 kDa

Background

The DNA mismatch repair system (MMR) repairs post-replication DNA, inhibits recombination between nonidentical DNA sequences, and induces both checkpoint and apoptotic responses following certain types of DNA damage. MSH2 (MutS homologue 2) forms the hMutS-α dimer with MSH6 and is an essential component of the mismatch repair process.

Research Area

Epigenetics and Nuclear Signaling