Summary
| Production Name | CDK4 Rabbit Monoclonal Antibody |
| Description | Recombinant Rabbit Monoclonal antibody |
| Host | Rabbit |
| Application | WB |
| Reactivity | Human,Mouse |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG |
| Clonality | Monoclonal Antibody |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Purification | Affinity Purified |
Immunogen
| Gene Name | CDK4 |
| Alternative Names | CMM3; PSK-J3 |
| Gene ID | 1019 |
| SwissProt ID | P11802 |
Application
| Dilution Ratio | WB: 1/500-1/1000 |
| Molecular Weight | Calculated MW: 34 kDa; Observed MW: 34 kDa |
Background
Cyclin-dependent kinase activity is regulated by T-loop phosphorylation (Thr172 in the case of CDK4), by the abundance of their cyclin partners, and by association with CDK inhibitors of the Cip/Kip or INK family of proteins. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.
Research Area
Cell Biology
