WAVE 1 Rabbit Monoclonal Antibody

WAVE 1 Rabbit Monoclonal Antibody

Size1:50μl Price1:$158
Size2:100μl Price2:$288
Size3:500μl Price3:$1200 SKU: AMRe02770 Category: Rabbit Monoclonal Antibody Tags: , , , , , ,

Datasheet

Summary

Production Name

WAVE 1 Rabbit Monoclonal Antibody

Description

Recombinant Rabbit Monoclonal antibody

Host

Rabbit

Application

WB

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purified

 

Immunogen

Gene Name

WASF1

Alternative Names

WAVE; SCAR1; WAVE1

Gene ID

8936

SwissProt ID

Q92558

 

Application

Dilution Ratio

WB: 1/500-1/1000

Molecular Weight

Calculated MW: 62 kDa; Observed MW: 90 kDa

 

Background

Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex . As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes .

 

Research Area

Signal Transduction

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