SNRPD3 Rabbit Monoclonal Antibody-Rabbit Monoclonal Antibody-EnkiLife-Recombinant Proteins,Antibodies,Kits,Cell Biology

SNRPD3 Rabbit Monoclonal Antibody

Summary

Production Name	SNRPD3 Rabbit Monoclonal Antibody
Description	Recombinant Rabbit Monoclonal antibody
Host	Rabbit
Application	WB
Reactivity	Human,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification	Affinity Purified

Immunogen

Gene Name	SNRPD3
Alternative Names	SMD3; Sm-D3
Gene ID	6634
SwissProt ID	P62318

Application

Dilution Ratio	WB: 1/500-1/1000
Molecular Weight	Calculated MW: 14 kDa; Observed MW: 14 kDa

Background

Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346). Is also a component of the minor U12 spliceosome (PubMed:15146077). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing .

Research Area

Epigenetics and Nuclear Signaling