NOXA Rabbit Monoclonal Antibody

NOXA Rabbit Monoclonal Antibody

Size1:50μl Price1:$158
Size2:100μl Price2:$288
Size3:500μl Price3:$1200 SKU: AMRe02829 Category: Rabbit Monoclonal Antibody Tags: , , ,

Datasheet

Summary

Production Name

NOXA Rabbit Monoclonal Antibody

Description

Recombinant Rabbit Monoclonal antibody

Host

Rabbit

Application

WB

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purified

 

Immunogen

Gene Name

PMAIP1

Alternative Names

APR; ATL-derived; NOXA; Pmaip1; Protein Noxa

Gene ID

5366

SwissProt ID

Q13794

 

Application

Dilution Ratio

WB: 1/500-1/1000

Molecular Weight

Calculated MW: 6 kDa; Observed MW: 10 kDa

 

Background

Noxa is a pro-apoptotic Bcl-2 family protein that contains a single Bcl-2 homology (BH3) domain. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1.

 

Research Area

Cell Biology

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