Recombinant Human ECH1 (N-6His)

Recombinant Human ECH1 (N-6His)

Size1:10μg price1:$136
Size2:50μg price2:$378
Size3:500μg price3:$1890 SKU: PEH0549 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Human ECH1 (N-6His)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, Mitochondrial is produced by our E.coli expression system and the target gene encoding Thr34-Leu328 is expressed with a 6His tag at the N-terminus.

Accession #

Q13011

Host

E.coli

Species

Human

Predicted Molecular Mass

34.5 KDa

Buffer

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 8% Trehalose, 0.05% tween80, pH8.5.

Form

Liquid

Shipping

The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

 

 

 

Alternative Names

Delta(3;5)-Delta(2;4)-dienoyl-CoA isomerase; mitochondrial; ECH1

 

Background

Human delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase(ECH1) is a member of the hydratase/isomerase superfamily and contains a C-terminal peroxisomal targeting sequence and localizes to peroxisomes. ECH1 shows high sequence similarity to enoyl-CoA hydratases of several species, particularly within a conserved domain characteristic of these proteins. The rat orthologlocalizes to the matrix of both the peroxisome and mitochondria.It can isomerize 3-trans, 5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. ECH1 plays an important role in the auxiliary step of the fatty acid beta-oxidation pathway.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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