Rb Rabbit Monoclonal Antibody

Rb Rabbit Monoclonal Antibody

Size1:50μl Price1:$188
Size2:100μl Price2:$338
Size3:500μl Price3:$1200
SKU: AMRe02530 Category: Rabbit Monoclonal Antibody Tags: , , ,

Datasheet

Summary

Production Name

Rb Rabbit Monoclonal Antibody

Description

Recombinant Rabbit Monoclonal antibody

Host

Rabbit

Application

WB

Reactivity

Mouse

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purified

 

Immunogen

Gene Name

RB1

Alternative Names

RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110

Gene ID

5925

SwissProt ID

P06400

 

Application

Dilution Ratio

WB: 1/500-1/1000

Molecular Weight

Calculated MW: 106 kDa; Observed MW: 110 kDa

 

Background

Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression. Rb inactivation and subsequent cell cycle progression likely requires an initial phosphorylation by cyclin D-CDK4/6 followed by cyclin E-CDK2 phosphorylation. Specificity of different CDK/cyclin complexes has been observed in vitro and cyclin D1 is required for Ser780 phosphorylation in vivo.

 

Research Area

Cell Biology