Summary
Production Name | TRIB3 Rabbit Polyclonal Antibody |
Description | Primary antibody |
Host | Rabbit |
Application | WB |
Reactivity | Human |
Performance
Conjugation | Unconjugated |
Modification | Unmodified |
Isotype | IgG |
Clonality | Polyclonal Antibody |
Form | Liquid |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification | Affinity Chromatography |
Immunogen
Gene Name | TRIB3 |
Alternative Names | C20orf97; NIPK; SINK; SKIP3; TRB3; Trib3; Tribbles homolog 3; Tribbles pseudokinase 3; Tribbles3 |
Gene ID | 57761 |
SwissProt ID | Q96RU7 |
Application
Dilution Ratio | WB: 1/500-1/1000 |
Molecular Weight | Calculated MW: 40 kDa; Observed MW: 40 kDa |
Background
Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity.
Research Area
Signal Transduction