Summary
| Production Name | ATF5 Rabbit Polyclonal Antibody |
| Description | Primary antibody |
| Host | Rabbit |
| Application | WB,IHC |
| Reactivity | Human,Mouse,Rat |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG |
| Clonality | Polyclonal Antibody |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification | Affinity Chromatography |
Immunogen
| Gene Name | ATF5 |
| Alternative Names | ATF5; ATFX; Cyclic AMP-dependent transcription factor ATF-5; cAMP-dependent transcription factor ATF-5; Activating transcription factor 5; Transcription factor ATFx |
| Gene ID | 22809 |
| SwissProt ID | Q9Y$2D1 |
Application
| Dilution Ratio | WB: 1/500-1/1000 IHC: 1/50-1/100 |
| Molecular Weight | Calculated MW: 31 kDa; Observed MW: 31 kDa |
Background
ATF5 or Activating transcription factor 5, binds to cAMP inducible promoters and is involved in gene transcription. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. ATF5 plays a role in inhibition of nerve growth factor induced neuronal outgrowth and regulation of neurogenesis.
Research Area
Epigenetics and Nuclear Signaling
