USP10 Rabbit Polyclonal Antibody

USP10 Rabbit Polyclonal Antibody

Size1:50μl Price1:$168
Size2:100μl Price2:$300
Size3:500μl Price3:$1200
SKU: APRab00253 Category: Polyclonal Antibody Tags: , , ,

Datasheet

Summary

Production Name

USP10 Rabbit Polyclonal Antibody

Description

Primary antibody

Host

Rabbit

Application

WB

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification

Affinity Chromatography

 

Immunogen

Gene Name

USP10

Alternative Names

Deubiquitinating enzyme 10; UBPO; USP10

Gene ID

9100

SwissProt ID

Q14694

 

Application

Dilution Ratio

WB: 1/500-1/1000

Molecular Weight

Calculated MW: 87 kDa; Observed MW: 110 kDa

 

Background

Hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. Acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53.

 

Research Area

Cell Biology