Thioredoxin Reductase 1 Rabbit Polyclonal Antibody

Thioredoxin Reductase 1 Rabbit Polyclonal Antibody

Size1:50μl Price1:$168
Size2:100μl Price2:$300
Size3:500μl Price3:$1200
SKU: APRab01347 Category: Polyclonal Antibody Tags: , , ,

Datasheet

Summary

Production Name

Thioredoxin Reductase 1 Rabbit Polyclonal Antibody

Description

Primary antibody

Host

Rabbit

Application

WB

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification

Affinity Chromatography

 

Immunogen

Gene Name

TXNRD1

Alternative Names

TR; TR1; TXNR; TRXR1; GRIM-12

Gene ID

7296

SwissProt ID

Q16881

 

Application

Dilution Ratio

WB: 1/500-1/1000

Molecular Weight

Calculated MW: 71 kDa; Observed MW: 55 kDa

 

Background

Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.

 

Research Area

Signal Transduction