Summary
| Production Name | Polyclonal AntibodyPN1 Rabbit Polyclonal Antibody |
| Description | Primary antibody |
| Host | Rabbit |
| Application | WB |
| Reactivity | Human,Mouse |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG |
| Clonality | Polyclonal Antibody |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification | Affinity Chromatography |
Immunogen
| Gene Name | PABPN1 |
| Alternative Names | OPMD; PAB2; PABII; PABP2; PABP-2 |
| Gene ID | 8106 |
| SwissProt ID | Q86U42 |
Application
| Dilution Ratio | WB: 1/500-1/1000 |
| Molecular Weight | Calculated MW: 33 kDa; Observed MW: 49 kDa |
Background
Involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product. Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length. Increases the affinity of poly(A) polymerase for RNA.
Research Area
Epigenetics and Nuclear Signaling
