Axin 2 Rabbit Polyclonal Antibody

Axin 2 Rabbit Polyclonal Antibody

Size1:50μl Price1:$168
Size2:100μl Price2:$300
Size3:500μl Price3:$1200 SKU: APRab00181 Category: Polyclonal Antibody Tags: , , , , , ,

Datasheet

Summary

Production Name

Axin 2 Rabbit Polyclonal Antibody

Description

Primary antibody

Host

Rabbit

Application

WB

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification

Affinity Chromatography

 

Immunogen

Gene Name

AXIN2

Alternative Names

Axil; Axin like protein; Axin2; Axis inhibition protein 2; Conductin

Gene ID

8313

SwissProt ID

Q9Y$2T1

 

Application

Dilution Ratio

WB: 1/500-1/1000

Molecular Weight

Calculated MW: 94 kDa; Observed MW: 94 kDa

 

Background

Axin1 (Axis inhibition protein 1) and Axin2 are multidomain scaffold proteins that negatively regulate Wnt signaling. Axin1 interacts with APC, GSK-3β, Dvl, and β-catenin and promotes the GSK-3β-mediated phosphorylation and subsequent degradation of β-catenin .Down-regulates beta-catenin.

 

Research Area

Cell Biology

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