Summary
| Production Name | CD3 epsilon Rabbit Polyclonal Antibody |
| Description | Primary antibody |
| Host | Rabbit |
| Application | WB,IHC |
| Reactivity | Human |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG |
| Clonality | Polyclonal Antibody |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification | Affinity Chromatography |
Immunogen
| Gene Name | CD3E |
| Alternative Names | CD3E; T3E; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e |
| Gene ID | 916 |
| SwissProt ID | P07766 |
Application
| Dilution Ratio | WB: 1/500-1/1000 IHC: 1/50-1/100 |
| Molecular Weight | Calculated MW: 23 kDa; Observed MW: 23 kDa |
Background
The CD3 complex mediates signal transduction. When T cells encounter antigens via the T cell receptor (TCR), information about the quantity and quality of antigens is relayed to the intracellular signal transduction machinery . This activation process depends mainly on CD3 (Cluster of Differentiation 3), a multiunit protein complex that directly associates with the TCR. CD3 is composed of four polypeptides: ζ, γ, ε and δ.
Research Area
Immunology
