CNOT7 Rabbit Polyclonal Antibody-Polyclonal Antibody-EnkiLife-Recombinant Proteins,Antibodies,Kits,Cell Biology

CNOT7 Rabbit Polyclonal Antibody

Summary

Production Name	CNOT7 Rabbit Polyclonal Antibody
Description	Primary antibody
Host	Rabbit
Application	WB,IHC
Reactivity	Human,Mouse,Rat,Monkey

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Polyclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification	Affinity Purified

Immunogen

Gene Name	Cnot7
Alternative Names	CCR4-associated factor 1; CAF-1
Gene ID	18983
SwissProt ID	Q60809

Application

Dilution Ratio	WB: 1/500-1/1000 IHC: 1/50-1/100
Molecular Weight	Calculated MW: 33 kDa; Observed MW: 33 kDa

Background

Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.

Research Area

Epigenetics and Nuclear Signaling