WDR5 Rabbit Polyclonal Antibody-Polyclonal Antibody-EnkiLife-Recombinant Proteins,Antibodies,Kits,Cell Biology

WDR5 Rabbit Polyclonal Antibody

Summary

Production Name	WDR5 Rabbit Polyclonal Antibody
Description	Primary antibody
Host	Rabbit
Application	WB
Reactivity	Human,Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Polyclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	Affinity Chromatography

Immunogen

Gene Name	WDR5
Alternative Names	WDR5; BIG3; WD repeat-containing protein 5; BMP2-induced 3-kb gene protein
Gene ID	11091
SwissProt ID	P61964

Application

Dilution Ratio	WB: 1/500-1/1000
Molecular Weight	Calculated MW: 37 kDa; Observed MW: 37 kDa

Background

Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.

Research Area

Epigenetics and Nuclear Signaling