Caspase 1 Rabbit Polyclonal Antibody

Caspase 1 Rabbit Polyclonal Antibody

Size1:50μl Price1:$150
Size2:100μl Price2:$280
Size3:500μl Price3:$1200
SKU: APRab03841 Category: Polyclonal Antibody Tags: , , , , ,

Datasheet

Summary

Production Name

Caspase 1 Rabbit Polyclonal Antibody

Description

Primary antibody

Host

Rabbit

Application

WB,IHC,ELISA

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification

Affinity Purified

 

Immunogen

Gene Name

CASP1

Alternative Names

CASP1; IL1BC; IL1BCE; Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45

Gene ID

834

SwissProt ID

P29466

 

Application

Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Molecular Weight

Calculated MW: 45 kDa; Observed MW: 45 kDa

 

Background

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

 

Research Area

Cell Biology