Phospho-IRS1 (Ser639) Rabbit Polyclonal Antibody

Phospho-IRS1 (Ser639) Rabbit Polyclonal Antibody

Size1:50μl Price1:$168
Size2:100μl Price2:$300
Size3:500μl Price3:$1200 SKU: APRab00830 Category: Polyclonal Antibody Tags: , , , , ,

Datasheet

Summary

Production Name

Phospho-IRS1 (Ser639) Rabbit Polyclonal Antibody

Description

Primary antibody

Host

Rabbit

Application

WB,IHC,ELISA

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Phosphorylated

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification

Affinity Chromatography

 

Immunogen

Gene Name

IRS1

Alternative Names

IRS1; Insulin receptor substrate 1; IRS-1

Gene ID

3667

SwissProt ID

P35568

 

Application

Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Molecular Weight

Calculated MW: 132 kDa; Observed MW: 150 kDa

 

Background

May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit .

 

Research Area

Tags & Cell Markers

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