CD130 Rabbit Polyclonal Antibody

CD130 Rabbit Polyclonal Antibody

Size1:50μl Price1:$150
Size2:100μl Price2:$280
Size3:500μl Price3:$1200 SKU: APRab00957 Category: Polyclonal Antibody Tags: , , , ,

Datasheet

Summary

Production Name

CD130 Rabbit Polyclonal Antibody

Description

Primary antibody

Host

Rabbit

Application

WB,IHC

Reactivity

Human,Mouse

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification

Affinity Purified

 

Immunogen

Gene Name

IL6ST

Alternative Names

Interleukin-6 receptor subunit beta ,IL-6 receptor subunit beta,IL-6R subunit beta,IL-6R-beta, IL-6RB,CDw130

Gene ID

3572

SwissProt ID

P40189

 

Application

Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100

Molecular Weight

Calculated MW: 104 kDa; Observed MW: 130-140kDa

 

Background

The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates the intracellular JAK-MAPK and JAK-STAT3 signaling pathways.

 

Research Area

Cell Biology

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